Best way to lay out graphic illustrations on page?

Hi,

I’m interested in developing a medical educational app using a splitviewcontroller for the ipad. What I’m not sure about is how to lay out illustrations and text and even animations on to each page on the detail side. One option would be to use html pages but havent experimented with html5 animating techniques yet. One other option is to use photoshop to design each page and overlay animations. Can anyone make some suggestions?

Thank you.